Aad Withaar

Alumnus

Throughout his doctoral tenure Aad’s research focused on the development of a small animal model of heart failure with preserved ejection fraction (HFpEF), enabling development and translation of innovative therapeutic strategies for treatment of HFpEF. Currently, Aad continues his academic career as a postdoctoral researcher. Our ongoing research is dedicated to unravel the potential of cardiometabolic treatments for HFpEF.

Contact details

Current activities

His research is focuses on novel intervention strategies in a cardiometabolic mouse model for HFpEF. Besides he studies the role that sex-differences play in humans and mice in the pathogenesis of heart failure.

My projects

SHE-PREDICTS HF

Predicting new-onset heart failure in women

Adiposity in Heart Failure with Preserved Ejection Fraction

Epicardial fat can cause heart failure with preserved ejection fraction.

My publications

The Cardioprotective Effects of Semaglutide Exceed Those of Dietary Weight Loss in Mice With HFpEF

Withaar C, Meems LMG, Nollet EE, Schouten EM, Schroeder MA, Knudsen LB, Niss K, Madsen CT, Hoegl A, Mazzoni G, van der Velden J, Lam CSP, Silljé HHW, de Boer RA. The Cardioprotective Effects of Semaglutide Exceed Those of Dietary Weight Loss in Mice with HFpEF. JACC Basic Transl Sci. 2023 Jul 26;8(10):1298-1314. doi: 10.1016/j.jacbts.2023.05.012. PMID: 38094687; PMCID: PMC10714176.

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