Nienke Stege

Alumnus

Nienke Stege received her bachelor’s degree in Biology (2016) and master’s degree in Biomedical Sciences (2018) from the University of Groningen. In December 2018, she started working as a PhD candidate at the Experimental Cardiology department of the UMCG, under the supervision of prof. dr. Rudolf de Boer and dr. Herman Silljé. Her current study focuses on the investigation of PLN-R14del cardiomyopathy.

Contact details

Current activities

Nienke is working on a project that concerns both basic science and pre-clinical research on PLN-R14del cardiomyopathy. She is investigating the disease mechanism  and new treatment strategies in an in vivo model for PLN-R14del cardiomyopathy.

My projects

PLN cardiomyopathy

Investigating and treating phospholamban cardiomyopathy

My publications

DWORF Extends Life Span in a PLN-R14del Cardiomyopathy Mouse Model by Reducing Abnormal Sarcoplasmic Reticulum Clusters

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The phospholamban p.(Arg14del) pathogenic variant leads to cardiomyopathy with heart failure and is unreponsive to standard heart failure therapy

Tim R Eijgenraam, Bastiaan J Boukens, Cornelis J Boogerd, Marloes Schouten, Cees W A van de Kolk, Nienke M Stege, Wouter P Te Rijdt, Edgar T Hoorntje, Paul A van der Zwaag, Eva van Rooij, J Peter van Tintelen, Maarten P van den Berg, Peter van der Meer, Jolanda van der Velden, Herman H W Silljé, Rudolf A de Boer. Sci Rep. 2020

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